We have extensive experience in the characterization of materials and chemistries used in stents. Although nitinol is a commonly used alloy for stents, we have experience in the characterization of alternative metal alloys (e.g. stainless steel and MP35N). FDA has issued guidance on nickel rich implants where we have helped companies evaluate their materials. We have expertise in the following characterization studies:

• Auger Electron Spectroscopy to evaluate surface chemistries and determine depth profiles of select elements
• Corrosion susceptibility using ASTM F2129
• Nickel ion release testing through leaching and analysis by ICP

Additionally, we have experience in failure analysis of metal alloys used in stent applications including fatigue resistance and hydrogen embrittlement.